Sim3C: simulation of Hi-C and Meta3C proximity ligation sequencing technologies
نویسندگان
چکیده
منابع مشابه
Sim3C: simulation of Hi-C and Meta3C proximity ligation sequencing technologies
Background Chromosome conformation capture (3C) and Hi-C DNA sequencing methods have rapidly advanced our understanding of the spatial organization of genomes and metagenomes. Many variants of these protocols have been developed, each with their own strengths. Currently there is no systematic means for simulating sequence data from this family of sequencing protocols, potentially hindering the ...
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ژورنال
عنوان ژورنال: GigaScience
سال: 2017
ISSN: 2047-217X
DOI: 10.1093/gigascience/gix103